Keytruda May Bring Hope for Mesothelioma Patients

Mesothelioma patients may benefit from the U.S. Food and Drug Administration’s (FDA) recent approval of Keytruda (pembrolizumab), manufactured by Merck. Keytruda is an immunotherapy drug designed to treat advanced non-small cell lung cancer (NSCLC).

Keytruda works by obstructing a cellular pathway that allows cancer cells to spread. Called PD-1/PD-L1, the pathway consists of proteins existing in some cancer cells and on the body’s immune cells. By shutting down this pathway, Keytruda may empower the body’s immune system to tackle cancer cells on its own.

Keytruda has already been approved for use in advanced melanoma patients. Opdivo (nivolumab), another drug that blocks the PD-1/PD-L1 pathway, received FDA approval for treating squamous non-small cell lung cancer (a type of NSCLC) earlier this year.

Follow Up Clinical Trial Now Underway for Immunotherapy Drug Keytruda in Mesothelioma Patients

Mesothelioma is a rare cancer with one established cause — asbestos exposure. In 20 to 40 percent of mesothelioma tumors, a protein exists that is similar to the PD-1/PD-L1 protein found in NSCLC tumors. If Keytruda works for NSCLC, that success could open the door for the development of similar treatments for mesothelioma patients.

Keytruda is promising enough that the FDA has given it accelerated approval and granted its use with a companion diagnostic test that can detect PD-L1 expression in NSCLC. If PD-L1 expression is also found in mesothelioma patients, Keytruda may benefit them as well.

Keytruda has had many positive results in its early clinical trials. For mesothelioma patients, three out of four were helped by the drug. Tumors stopped growing in nearly half the patients and one in four mesothelioma tumors shrank 30 percent or more. A follow up clinical trial for Keytruda and mesothelioma patients is now underway.

Contact Waters Kraus Paul & Siegel to Learn More About Filing a Mesothelioma Lawsuit

If you (or a loved one) have been diagnosed with mesothelioma, contact us by email or call us at 800.226.9880 to speak with our asbestos lawyers, like Gary Paul and Scott Frost in our Los Angeles office, to learn more about how we can assist you and your family with a mesothelioma lawsuit.

What are my chances?

That’s the first question everyone asks. The truth is it’s impossible to know. But we can tell you this. Waters Kraus Paul & Siegel has what it takes to fight against big corporate interests and win. That’s why we’ve taken more mesothelioma trials to verdict than any other firm. And that’s why we’ve recovered more than $1.3 billion for clients like you. Do you think you have a case? Contact us now to speak with an attorney.

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